Anti-Platelet Therapy
نویسندگان
چکیده
منابع مشابه
Novel agents for anti-platelet therapy
Anti-platelet therapy plays an important role in the treatment of patients with thrombotic diseases. The most commonly used anti-platelet drugs, namely, aspirin, ticlopidine, and clopidogrel, are effective in the prevention and treatment of cardio-cerebrovascular diseases. Glycoprotein IIb/IIIa antagonists (e.g., abciximab, eptifibatide and tirofiban) have demonstrated good clinical benefits an...
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The P2Y(12) receptor on platelets with which ADP interacts has an important role in promoting platelet function and thereby platelet involvement in both haemostasis and thrombosis. Agents that act as antagonists at this receptor are thus likely to provide effective antithrombotic therapy, provided that there are no adverse effects on haemostasis. Here we describe the ADP receptor antagonists th...
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The term ‘Acute Coronary Syndrome’ (ACS) refers to a range of acute myocardial ischaemic states which include unstable angina, non ST segment elevation myocardial infarction (NSTEMI) and ST segment elevation myocardial infarction (STEMI). Despite significant advances in the diagnosis and management, ACS remains a significant global problem with very high mortality and morbidity. The pathogeneti...
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That the decision-making process in medicine is generally complex is comprehensible. Indeed, several factors need be considered when a medical procedure is performed or a therapeutic approach is used, such as the patient's characteristics, the complexity of the procedure, the drugs to be administered, the physician’s skill, and the setting. The difficulty is further increased when the available...
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INTRODUCTION Anti-platelet drugs are useful in preventing unwanted clots, but the complexities of platelet activation and clot formation are challenging. BACKGROUND Platelets can be activated by a variety of agents, including natural biomolecules, foreign materials, and drugs. Calcium mediates a number of the intracellular processs Once activated, platelets release factors that act on other c...
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ژورنال
عنوان ژورنال: Journal of Nihon University Medical Association
سال: 2014
ISSN: 0029-0424,1884-0779
DOI: 10.4264/numa.73.76